Inflammatory Bowel Disease ranges in severity for sufferers, affecting daily functioning and requiring diet, lifestyle and (sometimes) medication for management.
There’s no known cause for IBS. Theories held by different medical professionals include muscle contraction control in the intestines, inflammation, nervous system malfunction, imbalanced gut bacteria, infections and more.
Symptoms sometimes have no identified triggers. Other times, sufferers can find a link between certain foods, stress and even hormones.
Because CBD has proven effects on many of these potential causes – especially inflammation, bacterial infections and nervous system malfunctioning – it’s reasonable to believe that it may play a role in regulating the disorder.
It all starts with the connection between the endocannabinoid system and intestinal function/motility. Recent studies have found that the transmitters regulated by the endocannabinoid system are located throughout the human body. Some of these transmitters are responsible for gut function; when imbalanced, negative effects are likely to occur.
A study highlighting this was performed approximately one decade ago. The study found a link between IBS sufferers and clinical endocannabinoid deficiency, which relates back to the fact that the system directly impacts intestinal motility and function. When CBD was used to activate and regulate the endocannabinoid system, sufferers of IBS saw significant symptom improvement.
Another study (performed in 2011) found a link between nervous and immune system involvement and IBS. When CBD was used to treat IBS patients, regulation of gliosis in the nervous system (commonly associated with negative IBS effects) seemed possible, without the psychoactive and other common effects of traditional treatments or even medical marijuana.
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